A novel pseudo four component reaction involving homoenolate for the synthesis of gamma-aminobutyric acid (GABA) derivatives

Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/1017

Title:	A novel pseudo four component reaction involving homoenolate for the synthesis of gamma-aminobutyric acid (GABA) derivatives
Authors:	Vijay Nair, G Vimal Varghese Beneesh, P B Sinu, C R Suresh, E
Keywords:	Chalcones Glutamate Conjugate umpolung Butyrolactones Alpha,beta-unsaturated aldehydes Direct annulations Carbene-catalyzed reaction Stereoselective-synthesis Enals
Issue Date:	2010
Publisher:	Royal Society of Chemistry
Citation:	Organic & Biomolecular Chemistry 8(4):761-764;2010
Abstract:	Homoenolate generated from alpha,beta-unsaturated aldehydes by NHC catalysis underwent facile addition to conjugated sulfonimines, generated in situ, and subsequent methanolysis to afford protected GABA derivatives stereoselectively and in high yields, thus constituting a novel pseudo four component reaction.
URI:	http://ir.niist.res.in:8080/jspui/handle/123456789/1017
ISSN:	1477-0520
Appears in Collections:	2010

Files in This Item:

File	Description	Size	Format
2010_ 0026.pdf Restricted Access		264.62 kB	Adobe PDF	View/Open Request a copy

DSpace JSPUI