Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/1018
Title: Isolation, characterization and quantification of tricin and flavonolignans in the medicinal rice njavara (Oryza sativa L.), as compared to staple varieties
Authors: Smitha, M
Parvathy, R
Shalini, V
Helen, A
Jayalekshmy, A
Keywords: Sugarcane tops
Lignocellulosic biomass
Bioethanol
Microcrystalline cellulose
Saccharomyces-cerevisiae
Lignocellulosic ethanol
Wheat-straw
Formic-acid
Rice straw
Hydrolysis
Flavonolignans
Njavara
Tricin 4 ′ -O-( erythro - β - guaiacylglyceryl) ether
Tricin 4 ′ -O-( threo - β -guaiacylglyceryl) ether
Issue Date: 2011
Publisher: Springer
Citation: Plant Foods for Human Nutrition 66(1):91-96;Mar 2011
Abstract: Njavara is an important medicinal rice variety of Kerala, India, widely used in Ayurveda as a 'health food' and in the treatment of rheumatoid arthritis, paralysis, neurodegenerative diseases and in rejuvenation therapy. Phytochemical investigations and spectroscopic studies of the diethyl ether fraction of methanolic extract of Njavara Black (NB) rice bran gave three important compounds namely, tricin and two rare flavonolignans- tricin 4'-O-(erythro-beta-guaiacylglyceryl) ether and tricin 4'-O-(threo-beta-guaiacylglyceryl) ether. The EC(50) values of these compounds in DPPH system were 90.39, 352.04 and 208.1 mu g/ml, respectively. Quantification of the compounds by HPLC in NB and staple, non-medicinal rice varieties Sujatha (SJ) and Palakkadan Matta (PM) showed that tricin is present 39.64 and 16.12 fold higher in NB, compared to SJ and PM, respectively. This is the first report on the occurrence of tricin at significantly higher levels in Njavara and occurrence of the two flavonolignans in Oryza sativa species. Of the three compounds, tricin and the threo- form of flavonolignan showed anti-inflammatory effect of > 65% after 5 h, at 2 mg/kg, in carrageenan-induced, paw edema experiments in rats. The results of the study corroborate with the preferential use of Njavara in indigenous medicine, over staple varieties.
URI: http://ir.niist.res.in:8080/jspui/handle/123456789/1018
ISSN: 0921-9668
Appears in Collections:2011

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