Synthesis of novel zerumbone derivatives via regioselective palladium catalyzed decarboxylative coupling reaction: a new class of alpha-glucosidase inhibitors

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DC Field	Value	Language
dc.contributor.author	Ajish, K R	-
dc.contributor.author	Dhanya, B P	-
dc.contributor.author	Nayana Joseph	-
dc.contributor.author	Priya Rani, M	-
dc.contributor.author	Raghu, K G	-
dc.contributor.author	Vineetha, V P	-
dc.contributor.author	Radhakrishnan, K V	-
dc.date.accessioned	2014-05-26T08:42:35Z	-
dc.date.available	2014-05-26T08:42:35Z	-
dc.date.issued	2014	-
dc.identifier.citation	Tetrahedron Letters 55(3):665-670;15 Jan 2014	en_US
dc.identifier.issn	0040-4039	-
dc.identifier.uri	http://ir.niist.res.in:8080/jspui/handle/123456789/1454	-
dc.description.abstract	A new strategy for the synthesis of novel zerumbone derivatives via a regioselective palladium catalyzed decarboxylative coupling reaction using arene carboxylic acids is described. The current methodology involves the repositioning of endocyclic double bond to exocyclic double bond of zerumbone. Preliminary in vitro analysis revealed that most of the newly synthesized derivatives are potent alpha-glucosidase enzyme inhibitors.	en_US
dc.language.iso	en	en_US
dc.publisher	Elsevier Science	en_US
dc.subject	Zerumbone	en_US
dc.subject	Zingiber zerumbet	en_US
dc.subject	Palladium	en_US
dc.subject	Decarboxylative coupling	en_US
dc.subject	Alpha-Glucosidase inhibitors	en_US
dc.title	Synthesis of novel zerumbone derivatives via regioselective palladium catalyzed decarboxylative coupling reaction: a new class of alpha-glucosidase inhibitors	en_US
dc.type	Article	en_US
Appears in Collections:	2014

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