Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/1460
Title: Microwave assisted synthesis of novel imidazolopyridinyl indoles as potent antioxidant and antimicrobial agents
Authors: Biradar, J S
Rajesab, P
Sasidhar, B S
Keywords: Imidazolopyridinyl indoles
Antioxidants
Antimicrobials
Issue Date: 2014
Publisher: Hindawi Publishing Corporation
Citation: Journal of Chemistry:Article ID 579612; 2014
Abstract: We describe herein the design, synthesis, and pharmacological evaluation of novel series of imidazolopyridinyl indole analogues as potent antioxidants and antimicrobials. These novel compounds (3a-i) were synthesized by reacting 3,5-disubstituted-indole-2-carboxylic acid (1a-i) with 2,3-diamino pyridine (2) in excellent yield. The novel products were confirmed by their IR, H-1 NMR, C-13 NMR, mass spectral, and analytical data. These compounds were screened for their antioxidant and antimicrobial activities. Among the compounds tested, 3a-d showed the highest total antioxidant capacity, scavenging, and antimicrobial activities. Compounds 3c-d and 3g-h have shown excellent ferric reducing activity.
URI: http://ir.niist.res.in:8080/jspui/handle/123456789/1460
ISSN: 2090-9063
Appears in Collections:2014

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