Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1488
Title: Rhodium(III) catalyzed synthesis of isoquinolone fused azabicycles through C-H activation of N-pivaloyloxy benzamides
Authors: Praveen, P
Jijy, E
Aparna, P S
Viji, S
Radhakrishnan, K V
Keywords: Rhodium
Isoquinolone
Bicyclic olefin
C–H activation
Benzamide
Issue Date: 2014
Publisher: Elsevier
Citation: Tetrahedron Letters 55(4):916–920;22 Jan 2014
Abstract: Herein we describe an efficient one pot strategy toward highly functionalized isoquinolone fused azabicycles having great synthetic potential via C-H activation of N-pivaloyloxy benzamides under very mild conditions. The reaction is accomplished at room temperature within one hour in good to excellent yields and is found to be compatible with a range of diazabicyclic olefins and benzamides. The present strategy offers an easy route for the synthesis of biologically relevant compounds which possess multiple points for divergent synthesis. N-N bond cleavage of synthesized compounds may enable their significant role as effective precursors for the preparation of diaminocyclopentane fused isoquinolones.
URI: http://ir.niist.res.in:8080/jspui/handle/123456789/1488
ISSN: 0040-4039
Appears in Collections:2014

Files in This Item:
File Description SizeFormat 
2014-35.pdf4.35 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.