Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/1659
Title: Parmotrema tinctorum exhibits antioxidant, antiglycation and inhibitory activities against aldose reductase and carbohydrate digestive enzymes: An in vitro study
Authors: Salin Raj, P
Prathapan, A
Jomon, S
Antu, K A
Riya, M P
Preetha Rani, M R
Biju, H
Priya, S
Raghu, K G
Keywords: Lichen
Issue Date: 2014
Publisher: Taylor & Francis
Citation: Natural Product Research 28(18):1480-4;Sep 2014
Abstract: This study evaluated the inhibitory potential of ethyl acetate extract of Parmotrema tinctorum (PTEE), an edible lichen, against aldose reductase (AR) and carbohydrate digestive enzymes such as alpha-glucosidase and alpha-amylase. It was also screened for antioxidant activities by using DPPH, ABTS, superoxide and hydroxyl radical-scavenging assays. PTEE exhibited alpha-glucosidase, alpha-amylase and AR inhibition along with significant antiglycation potential with an estimated IC50 value of 58.45±1.24, 587.74±3.27, 139.28±2.6 and 285.78±1.287mug/mL, respectively. Antioxidant activity of PTEE against DPPH (IC50 396.83±2.98mug/mL), ABTS (151.34±1.79mug/mL), superoxide (30.29±1.17mug/mL) and hydroxyl (35.42±1.22mug/mL) radicals suggests the antioxidant potential of P. tinctorum. Significant antioxidant activity and inhibitory potential against carbohydrate digestive enzymes and AR suggest that P. tinctorum can be developed as functional food/nutraceuticals for diabetes after detailed study.
ISSN: 1478-6427
Appears in Collections:2014

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