Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/2613
Title: Antibacterial Activity of Kauranes from Annona squamosa L. Pericarp
Authors: Beena Joy
Sobhana, D
Keywords: A. squamosa
Annonaceae
Antibacterial activity
Pericarp
Issue Date: 2007
Publisher: Asian Publication Corporation
Citation: Asian Journal of Chemistry ;19(4):2773-2778)
Abstract: Bioactivity directed fractionation and isolation of active principles from the pericarp of Annona squamosa yielded three kauranes namely, (-)-ent-kaur-17-acetoxy, 19-oic acid, 16α, 17-dihydroxy-ent-kauran-19- oic acid and (-)-ent-kaur-17, 19-dioic acid. These compounds were tested against two bacteria, Staphylococus aureus (MTCC 737, S.N. Saxena, Staphlococcus Institute of Microbial Technology) and Escherichia. coli (MTCC 2991, N. Goel, Enterobacteriaceae, Institute of Microbial Technology). 16α, 17-Dihydroxy-ent-kauran-19-oic acid and (-)-entkaur- 17, 19-dioic acid at 100 μg and 500μg, respectively, showed more activity towards Escherichia. coli than the antibiotic, ampicillin at 500 μg and these kaurenes do not show promising activity towards Staphylococcus aureus, when compared with the standard drug, gentamycin. Here, we report the bioactivity directed fractionation, isolation and identification of the active principles by IR, NMR, MS and by the chemical conversions of the active compounds
URI: http://hdl.handle.net/123456789/2613
Appears in Collections:2007

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