Metal-Free Trans-Aziridination of Zerumbone: Synthesis and Biological Evaluation of Aziridine Derivatives of Zerumbone

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Title:	Metal-Free Trans-Aziridination of Zerumbone: Synthesis and Biological Evaluation of Aziridine Derivatives of Zerumbone
Authors:	Greeshma, G Dhanya, B P Saranya, J Reshmitha, T R Baiju, T V Meenu, M T Mangalam S Nair Nisha, P Radhakrishnan, K V
Keywords:	Zerumbone Hypervalent compounds Nitrogen heterocycles Small ring systems Sulfonamides
Issue Date:	8-Jun-2017
Publisher:	Wiley
Citation:	European Journal of Organic Chemistry, (21):3072-3077
Abstract:	Herein, we describe a metal-free, iodosobenzene diacetate mediated trans-aziridination of zerumbone by the direct use of sulfonamides. Preliminary in vitro screening showed that the synthesized compounds had better antiproliferative and antidiabetic activities than the parent compound zerumbone.
URI:	http://hdl.handle.net/123456789/2950
Appears in Collections:	2017

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