Gold Nanoparticle Patterned on PANI Nanowire Modified Transducer for the Simultaneous Determination of Neurotransmitters in Presence of Ascorbic Acid and Uric Acid

Abstract

In the present work, we have electrochemically deposited polyaniline nanowires (PANIS) on glassy carbon electrode (GCE) from its monomer liquid crystalline template of anilinium-3-pentadecyl phenyl sulphonic acid (An1 PDPSA2). Further, electrode was modified by the electrochemical patterning of gold nanoparticles on the PANIS/GCE (PANIS/Au/GCE) by electrodeposition through chronoamperometry. Modified electrode characterized by electrochemical impedance, morphology, XRD, electroactive surface area, and later demonstrated its efficacy for the individual and simultaneous sensing of dopamine, ascorbic acid, serotonin, and uric acid. Finally, its performance in the real sample (blood serum) was evaluated. The superior electrocatalytic performance with higher sensitivity suggested that the modified electrode can be used as an excellent transducer for the sensing of neurotransmitters.