Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/3120
Title: Lewis Acid Promoted Regioselective Double Hydro(hetero)arylation of 6,6′-Dialkyl-Substituted Pentafulvenes: A Facile Approach to Bisindole Derivatives
Authors: Sasikumar, P
Prabha, B
Chand, S S
Aswathy, M
Madhukrishnan, M
Preethanuj, P
Suresh, E
Jaroschik, F
Radhakrishnan, K V
Keywords: Fulvenes
C–C coupling
Hydro(hetero)arylation
Lewis acids
Nitrogen heterocycles
Issue Date: 17-Aug-2017
Publisher: Wiley
Citation: European Journal of Organic Chemistry, 2017(30):4469-4474
Abstract: A Lewis acid catalyzed double hydro(hetero)arylation of alkyl-substituted pentafulvenes for the synthesis of bisindolesubstituted cyclopentenoids has been developed. The scope of the reaction was explored with a wide range of indoles and pentafulvenes, and mechanistic insights were obtained. In addi-tion, we have also demonstrated a hydro(hetero)arylation–dehydroxylation reaction of 2-hydroxy-substituted pentafulvenes to afford bisindole derivatives with isoprenyl-substituted cyclopentene moieties.
URI: http://10.10.100.66:8080/xmlui/handle/123456789/3120
Appears in Collections:2017



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