Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/3253
Title: Molecular Advances in Microbial Aminopeptidases
Authors: Arya Nandan
Nampoothiri, K M
Keywords: Aminopeptidases
Metalloproteases
Gene cloning
Protein engineering
Thermostability
Issue Date: Dec-2017
Publisher: Elsevier
Citation: Bioresource Technology, 245(Part B):1757-1765
Abstract: Aminopeptidases are exopeptidases that catalyze the hydrolysis of amino acid residues from the N terminus of peptides and proteins. They are widely and diversely used for protein hydrolysis in industrial and research applications. They form a large enzyme family in microorganisms and most of the sequenced microbial genomes contain several aminopeptidase coding genes. Various approaches are being used to enhance the yield and desired properties of these enzymes to make it more suited for industrial applications. Novel aminopeptidases are being developed by site directed mutagenesis and recombinant DNA technology with improved substrate specificity and stability. This review focuses on its classification and recent advancements in the molecular studies pertaining to this enzyme.
URI: http://10.10.100.66:8080/xmlui/handle/123456789/3253
Appears in Collections:2017



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.