Chloroform as a carbon monoxide source in palladium-catalyzed synthesis of 2-amidoimidazo [1,2-a]pyridines

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Title:	Chloroform as a carbon monoxide source in palladium-catalyzed synthesis of 2-amidoimidazo [1,2-a]pyridines
Authors:	Nitha, P R Manu, M Joseph Greeshma, Gopalan Maiti, K K Radhakrishnan, K V Das, Parthasarathi
Issue Date:	Aug-2018
Publisher:	The Royal Society of Chemistry
Citation:	Organic & Biomolecular Chemistry, 16(35):6430–6437
Abstract:	A palladium-catalyzed aminocarbonylation strategy exploiting chloroform as a CO source has been developed for the synthesis of biologically potent 2-amidoimidazopyridine scaffolds. The aminocarbonylation reaction was found to be general with a range of amines and substituted imidazopyridines. Preliminary biological evaluation of cytotoxicity on selected examples provides scope for future investigations.
URI:	http://10.10.100.66:8080/xmlui/handle/123456789/3273
Appears in Collections:	2018

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