Please use this identifier to cite or link to this item:
Title: Facile Diastereoselective Synthesis of Highly Substituted Alkylene‐oxetanes from 3‐Alkyl Allenoates and Diaryl 1,2‐Diones/α‐Ketoamides Mediated by DBU
Authors: Krishnan, J
Mayadevi, T S
Varughese, S
Vijay Nair
Keywords: Zwitterions
Oxygen heterocycles
Issue Date: 21-Feb-2019
Publisher: Wiley
Citation: European Journal of Organic Chemistry; 7:1557-1561
Abstract: A facile tertiary amine‐mediated [2+2] annulation reaction of 3‐alkyl allenoates, and diaryl 1,2‐diones leading to diastereoselective synthesis of highly substituted alkylene‐oxetane derivatives is reported. The reaction was further extended to α‐ketoamides. The obtained amide‐appended oxetanes were transformed to 5‐methylene‐1H‐pyrrol‐2(5H)‐one derivatives with potential biological activity.
Appears in Collections:2019

Files in This Item:
File Description SizeFormat 
Facile Diastereoselective-Krishnan_et_al-2019-European_Journal_of_Organic_Chemistry.pdf1.11 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.