Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/3372
Title: Facile Diastereoselective Synthesis of Highly Substituted Alkylene‐oxetanes from 3‐Alkyl Allenoates and Diaryl 1,2‐Diones/α‐Ketoamides Mediated by DBU
Authors: Krishnan, J
Mayadevi, T S
Varughese, S
Vijay Nair
Keywords: Zwitterions
Allenes
Cycloaddition
Oxygen heterocycles
Issue Date: 21-Feb-2019
Publisher: Wiley
Citation: European Journal of Organic Chemistry; 7:1557-1561
Abstract: A facile tertiary amine‐mediated [2+2] annulation reaction of 3‐alkyl allenoates, and diaryl 1,2‐diones leading to diastereoselective synthesis of highly substituted alkylene‐oxetane derivatives is reported. The reaction was further extended to α‐ketoamides. The obtained amide‐appended oxetanes were transformed to 5‐methylene‐1H‐pyrrol‐2(5H)‐one derivatives with potential biological activity.
URI: https://onlinelibrary.wiley.com/doi/10.1002/ejoc.201801747
http://10.10.100.66:8080/xmlui/handle/123456789/3372
Appears in Collections:2019

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