I-2/tbhp Mediated Diastereoselective Synthesis of Spiroaziridines

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DC Field	Value	Language
dc.contributor.author	Ashitha, K T	-
dc.contributor.author	Vinaya, P P	-
dc.contributor.author	Krishna, A	-
dc.contributor.author	Vincent, D C	-
dc.contributor.author	Jalaja, R	-
dc.contributor.author	Varughese, S	-
dc.contributor.author	Somappa, S B	-
dc.date.accessioned	2021-03-30T10:44:32Z	-
dc.date.available	2021-03-30T10:44:32Z	-
dc.date.issued	2020-02-04	-
dc.identifier.citation	Organic & Biomolecular Chemistry; 18(8):1588-1593	en_US
dc.identifier.uri	https://pubs.rsc.org/en/content/articlepdf/2020/ob/c9ob02711d	-
dc.identifier.uri	http://hdl.handle.net/123456789/3701	-
dc.description.abstract	Eventhough spiroheterocycles are considered as emerging drug candidates, synthesis of spiroaziridines has not been well explored so far. Herein, we disclose an efficient I2/TBHP mediated diastereoselective synthesis of N-alkyl spiroaziridines from primary amines and easily accessible α,β-unsaturated ketones. The reaction is also compatible for the synthesis of 2-aroylaziridines.	en_US
dc.language.iso	en	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.subject	TBHP	en_US
dc.subject	diastereoselective	en_US
dc.subject	spiroaziridines	en_US
dc.title	I-2/tbhp Mediated Diastereoselective Synthesis of Spiroaziridines	en_US
dc.type	Article	en_US
Appears in Collections:	2020

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