Please use this identifier to cite or link to this item: http://localhost:8080/xmlui/handle/123456789/4555
Title: Copper-Catalyzed Annulation of Electrophilic Benzannulated Heterocycles with 2-Aminopyridine and 2-Aminoquinoline: Direct Access toward Polyring-Fused Imidazo[1,2-a]pyridines
Authors: Babu, S A
Varsha, P V
Poulose, S
Varughese, S
John, J
Keywords: Benzannulated Heterocycles
2-Aminopyridine and 2-Aminoquinoline
Issue Date: 21-Jul-2023
Publisher: ACS Publications
Citation: The Journal of Organic Chemistry;88(14):10027-10039
Abstract: We have developed a direct method for the synthesis of polyring-fused imidazo[1,2-a]pyridines via a coppercatalyzed annulation of electrophilic benzannulated heterocycles with 2-aminopyridine and 2-aminoquinoline. From 3-nitroindoles and 2-aminopyridine, we could synthesize tetracenes, viz., indolefused imidazo[1,2-a]pyridines, and by starting from 2-aminoquinoline, we could generate pentacenes, viz., indolo-imidazo[1,2- a]quinolines. In addition, we could also extend the methodology toward the synthesis of benzothieno-imidazo[1,2-a]pyridines starting from 3-nitrobenzothiophene. Furthermore, the basic photophysical properties of these synthesized heteroacenes were evaluated.
Appears in Collections:2023

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