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Title: Advances in the Synthesis of Fused 1,2,3-Triazoles via a MCR-Intramolecular Azide-Alkyne Cycloaddition Approach
Authors: Rahul, P
Thomas, J
Dehaen, W
John, J
Keywords: 1,2,3-triazole
multicomponent reaction
intramolecular azide-alkyne cycloaddition
dipolar cycloaddition
Issue Date: 30-Dec-2022
Publisher: MDPI
Citation: Molecules;28(1): Article ID: 308
Abstract: The present review narrates several reports which deal with the synthesis of fused 1,2,3-triazole containing scaffolds following a sequential multicomponent reaction (MCR)—intramolecular azide-alkyne cycloaddition (IAAC) approach. The reviewed reactions were cleverly designed so as to incorporate azide and alkyne functionalities in the MCR product which was then subjected to IAAC. The review is divided into two sections based on the number of components in the multicomponent reaction. We have aimed at a critical discussion and also have highlighted either advantages or disadvantages of each methodology
Appears in Collections:2023

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