Oral Thin-films from Design to Delivery: A Pharmaceutical Viewpoint

Abstract

Stable drug-type tablets and capsules are painful to drink or chew for many pediatric and geriatric patients. Accurate dosing is also an issue for liquid orals (syrup, suspension, emulsion, and so on). Several fast-dissolving drug delivery systems have been designed to address these issues. One of the innovative methods for rapid drug delivery with self-administration without water or chewing is a thin polymer oral drug strip. Strip-forming polymers, plasticizers, active pharmaceutical ingredients, sweetening agents, saliva enhancing agents, flavoring agents, coloring agents, stabilizing and thickening agents are all used to form oral drug strips. The scope of oral thin films is expanded in this article.