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Title: | Engineering semi-permeable giant liposomes |
Authors: | Radhakrishnan, S Nair, K S Nandi, S Bajaj, H |
Issue Date: | 31-Oct-2023 |
Publisher: | Royal Society of Chemistry |
Citation: | Chemical Communications; 59(93):13863-13866 |
Abstract: | Giant unilamellar vesicles (GUVs) with a semi-permeable nature are prerequisites for constructing synthetic cells. Here we engineer semi-permeable GUVs by the inclusion of DOTAP lipid in vesicles. Diffusion of molecules of different charge and size across GUVs are reported. Control over size-selective permeability is demonstrated by modulating the DOTAP lipid composition in different lipid systems without reconstituting membrane proteins. Such semi-permeable GUVs have immense applications for constructing synthetic cells. |
URI: | https://pubs.rsc.org/en/content/articlelanding/2023/CC/D3CC04039A http://localhost:8080/xmlui/handle/123456789/4725 |
Appears in Collections: | 2023 |
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File | Description | Size | Format | |
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Engineering semi-permeable giant liposomes_RadhakrishnanS_Chemical Communication.pdf Restricted Access | 968.81 kB | Adobe PDF | View/Open Request a copy |
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