Antidiabetic and antioxidant potentials of spent turmeric oleoresin, a by-product from curcumin production industry

Abstract

To investigate the antidiabetic and antioxidant activity of spent turmeric oleoresin(STO). Methods: Antidiabetic activity of STO evaluated by α- amylase and α enzyme inhibition assays. The antioxidant capacity studied by DPPH. , ABTS., supe-ro xgilduec orsaiddiacsael scavenging and metal chelating activity methods. Results: The STO showed good antidiabetic wacittihv iatyn bIyC 5in0vhaibluiteins go kf e0y.7 e1n aznymd e0s.1 l6inked to type 2 diabetes, viz α-glucosidase and α-amylase 毺g/mL respectively. The IC50 values for DPPH. and ABTS. assay were 58.1 and 33 毺g/mL respectively. STO effectively scavenged the superoxide free radical with an IC50 value of 61.5毺g/mL and showed a moderate iron chelation property. Conclusions: The above study reveals that the spent turmeric oleoresin being wasted at present can be used as antioxidant and antidiabetic agent in food and neutraceutical products