Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/57
Title: Iodine assisted palladium catalyzed ring opening of bicyclic hydrazines with organoboronic acids: Sereoselective synthesis of functionalized cyclopentenes and alkylidene cyclopentenes
Authors: Anas, S
Jubi John
Sajisha, V S
Joshni John
Rani Rajan
Suresh, E
Radhakrishnan, K V
Keywords: Palladium catalyzed ring
Azabicyclic olefins
Hydrazinocyclopentene
Issue Date: 2007
Publisher: Royal Society of Chemistry, London
Citation: Organic and Biomolecular Chemistry 5:4010-4019;2007
Abstract: A Novel reactivity of organoboronic acids with bicyclic hydrazines leading to the stereoselective formation of trans-vicinal disubstituted cyclopentenes in good to excellent yield is discussed. The reaction of cyclopentadiene and fulvene derived azabicyclic alkenenes with organoboronic acids afforded the trans-3,4-disubstituted cyclopentenes and alkylidene cyclopentenes in good to excellent yields. The products, having a broad range of substituents, are important intermediated in the synthesis of a number of pharmaceutically important molecules.
URI: http://hdl.handle.net/123456789/57
Appears in Collections:2007

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