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dc.contributor.authorPrathapan, A-
dc.contributor.authorCherian, O L-
dc.contributor.authorNampoothiri, S V-
dc.contributor.authorMini, S-
dc.contributor.authorRaghu, K G-
dc.date.accessioned2013-11-20T10:21:29Z-
dc.date.available2013-11-20T10:21:29Z-
dc.date.issued2011-
dc.identifier.citationNatural Product Research 25(3):298-309;2011en_US
dc.identifier.issn1478-6419-
dc.identifier.urihttp://ir.niist.res.in:8080/jspui/handle/123456789/786-
dc.description.abstractSaraca ashoka is a widely used medicinal herb claimed to cure many diseases. This study investigated the antiperoxidative, free radical scavenging and xanthine oxidase (XO) inhibitory potential of the ethyl acetate fraction of S. ashoka flowers (SAF) and compared it with standard compounds like gallic acid, ascorbic acid, butylated hydroxyl toluene and allopurinol. The ethyl acetate fraction of SAF exhibited free radical scavenging activity against the 1,1-diphenyl-2-picrylhydrazyl radical and superoxide radical, along with hydroxyl radical scavenging activity. Lipid peroxidation inhibitory potential of SAF was studied using a linoleic acid emulsion system, which shows significant antioxidant potential. SAF also demonstrated significant XO (key enzyme linked to inflammation) inhibitory activity, which revealed its therapeutic potential as an antioxidant and XO inhibitor. HPLC profiling of the ethyl acetate fraction of SAF revealed that it contains ellagic acid as a major compound and thus the beneficial effects of this fraction may be due to the presence of this compound.en_US
dc.language.isoenen_US
dc.publisherTaylor & Francisen_US
dc.subjectHPLCen_US
dc.subjectPhenolicsen_US
dc.subjectEllagic aciden_US
dc.subjectLipid peroxidationen_US
dc.subjectXanthine oxidaseen_US
dc.subjectNtioxidant activityen_US
dc.subjectFlavonoidsen_US
dc.subjectAutoxidationen_US
dc.subjectMetabolismen_US
dc.subjectMechanismsen_US
dc.subjectDiseaseen_US
dc.titleInvitro antiperoxidative, free radical scavenging and xanthine oxidase inhibitory potentials of ethyl acetate fraction of Saraca ashoka flowersen_US
dc.typeArticleen_US
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