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Browsing by Author "Nisha, V M"

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Apigenin and quercetin ameliorate mitochondrial alterations by tunicamycin-induced ER stress in 3T3-L1 adipocytes

Nisha, V M; Anusree, S S; Priyanka, A; Raghu, K G (Springer, 2014)

Endoplasmic reticulum (ER) is an important organelle with functions like protein synthesis, folding, and calcium homeostasis. ER stress, a condition that dramatically affects protein folding homeostasis in cells, has been ...
Bilobalide Abates Inflammation, Insulin Resistance and Secretion of Angiogenic Factors Induced by Hypoxia in 3T3-L1 Adipocytes by Controlling NF-κB and JNK Activation

Priyanka, A; Sindhu, G; Shyni, G L; Preetha Rani, M R; Nisha, V M; Raghu, K G (Elsevier, 2017-01)

Obesity leads to inflammation and insulin resistance in adipose tissue. Hypoxia, observed in obese adipose tissue is suggested as a major cause of inflammation and insulin resistance in obesity. However, the role of hypoxia ...
Bilobalide Safeguards 3T3-L1 Adipocytes from Hypoxia Through Protecting Mitochondrial Bioenergetics, Biogenesis and Dynamics

Priyanka, A; Nair, A; Anusree, S S; Nisha, V M; Raghu, K G (Royal society of chemistry, 2016)

Natural products are the cornerstone of modern therapeutics. Bilobalide was found to be effective against hypoxia induced alterations in innate antioxidant status in our earlier study. Adipose tissue hypoxia in ...
In vitro antidiabetic and inhibitory potential of turmeric (Curcuma longa L)rhizome against cellular and LDL oxidation and angiotensin converting enzyme

Lekshmi, P C; Ranjith Arimboor; Nisha, V M; Nirmala Menon, A; Raghu, K G (spinger, 2014-12)

Turmeric (Curcuma longaL) rhizome extracts were evaluated for their antidiabetic, antihypertensive and antioxidant potentials.α-Glucosidase (0.4 μg/mL) andα-amylase (0.4μg/mL) inhibitory potential of turmeric ethyl acetate ...
Inhibitory effect of Terminalia chebula Retz. fruit extracts on digestive enzyme related to diabetes and oxidative stress

Indu Sasidharan; Sundaresan, A; Nisha, V M; Mahesh, S K; Raghu, K G; Jayamurthy, P (Informa, 2012)

Terminalia chebula fruit extracts were prepared sequentially with hexane, ethyl acetate, methanol and methanol– water (70:30) and tested for their α-glucosidase inhibitory and antioxidant potential. The study resulted in ...
Inhibitory Potential of Ginger Extracts Against Enzymes Linked to Type 2 Diabetes, Inflammation and Induced Oxidative Stress

Priya Rani, M; Padmakumari Amma, K P; Sankarikutty, B; Cherian, O L; Nisha, V M; Raghu, K G (Informa Health care, 2011-03)

Ginger (Zingiber officinale Roscoe) continues to be used as an important cooking spice and herbal medicine around the world. Gingerols, the major pungent components of ginger, are known to improve diabetes, including the ...
Polyphenol rich fruit pulp of Aegle marmelos (L.) Correa exhibits nutraceutical properties to down regulate diabetic complications — An in vitro study

Prathapan, A; Mahesh, S K; Nisha, V M; Sundaresan, A; Raghu, K G (Elsevier, 2012-10)

In the present study, methanolic extract of Aegle marmelos (L.) Correa fruit pulp (AME) was evaluated for various parameters relevant to diabetes such as antiperoxidative, free radical scavenging and inhibitory potentials ...
Preconditioning L6 muscle cells with Naringin ameliorates oxidative stress and increases glucose uptake

Dhanya, R; Arun, K B; Nisha, V M; Syama, H P; Nisha, P; Santhosh Kumar, T R; Jayamurthy, P (PLOS, 2015-07-06)

Enhanced oxidative stress contributes to pathological changes in diabetes and its complications. Thus, strategies to reduce oxidative stress may alleviate these pathogenic processes. Herein, we have investigated Naringin ...

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