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Browsing by Author "Reshmitha, T R"

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Comparison of Antidiabetic Potential of (+) and (-)-hopeaphenol, a Pair of Enantiomers Isolated from Ampelocissus indica (L.) and Vateria Indica Linn., with Respect to Inhibition of Digestive Enzymes and Induction of Glucose Uptake in L6 Myotubes

Sasikumar, P; Prabha, B; Reshmitha, T R; Veluthoor, S; Pradeep, A K; Rohit, K R; Dhanya, B P; Sivan, V V; Jithin, M M; Kumar, N A; Shibi, I G; Nisha, P; Radhakrishnan, K V (Royal society of chemistry, 2016)

The remarkable α-glucosidase inhibition exhibited by the acetone extract of the rhizome of Ampelocissus indica (L.) and stem bark of Vateria indica Linn. (IC50 23.2 and 1.47 μg mL−1) encouraged us to isolate the phytochemicals ...
Metal-Free Trans-Aziridination of Zerumbone: Synthesis and Biological Evaluation of Aziridine Derivatives of Zerumbone

Greeshma, G; Dhanya, B P; Saranya, J; Reshmitha, T R; Baiju, T V; Meenu, M T; Mangalam S Nair; Nisha, P; Radhakrishnan, K V (Wiley, 2017-06-08)

Herein, we describe a metal-free, iodosobenzene diacetate mediated trans-aziridination of zerumbone by the direct use of sulfonamides. Preliminary in vitro screening showed that the synthesized compounds had better ...
Morin Inhibits Proliferation of SW480 Colorectal Cancer Cells by Inducing Apoptosis Mediated by Reactive Oxygen Species Formation and Uncoupling of Warburg Effect

Thomas, S; Arun, K B; Syama, H P; Reshmitha, T R; Nisha, P (Frontiers Media, 2017-09-12)

The study under investigation focuses on in vitro antiproliferative efficacy of the flavonoid morin and the mechanisms by which it inhibits the growth of colon cancer using SW480 colon cancer cells with emphasis on Warburg ...
Musa Paradisiaca Inflorescence Induces Human Colon Cancer Cell Death by Modulating Cascades of Transcriptional Events

Arun, K B; Madhavan, A; Reshmitha, T R; Thomas, S; Nisha, P (Royal Society of Chemistry, 2018-01)

Colorectal cancer (CRC) is one of the leading causes of cancer death, and diet plays an important role in the etiology of CRC. Traditional medical practitioners in many South Asian countries use plantain inflorescence to ...
Nutraceutical Potential of Lycopene in Management of Oxidative Stress Mediated Disease Conditions

Reshmitha, T R (Agro Processing and Technology Division,National Institute for Interdisciplinary Science and Technology,Thiruvananthapuram.Under the Supervision of Dr.P.Nisha, 2022-08)
Screening of Musa balbisiana Colla. seeds for antidiabetic properties and isolation of apiforol, a potential lead, with antidiabetic activity

Gopalan, G; Prabha, B; Joe, A; Reshmitha, T R; Sherin, D R; Abraham, B; Sabu, M; Manojkumar, T K; Radhakrishnan, K V; Nisha, P (Wiley, 2019-03-30)

BACKGROUND: 'Phytonutrients' have been reported to exert an incredible impact on the healthcare system and offer medical benefits including the prevention or treatment of lifestyle-associated diseases. We chose one of the ...
Synthesis and In Vitro Evaluation of Zerumbone Pendant Derivatives: Potent Candidates for Anti-Diabetic and Anti-Proliferative Activities

Dhanya, B P; Greeshma, G; Reshmitha, T R; Saranya, J; Sharathna, P; Shibi, I G; Nisha, P; Radhakrishnan, K V (Royal Society of Chemistry, 2017-05-26)

A series of zerumbone pendant derivatives were synthesized and evaluated for their a-glucosidase, a-amylase and glycation inhibition activities. In our study, some of the derivatives showed potent inhibitory activity in ...

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