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Browsing by Author "Roschen Sasikumar"

Browsing by Author "Roschen Sasikumar"

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  • Chaos game representation for comparison of whole genomes 
    Jijoy Joseph; Roschen Sasikumar (Biomed central, 2006)
    Background: Chaos game representation of genome sequences has been used for visual representation of genome sequence patterns as well as alignment-free comparisons of sequences based on oligonucleotide frequencies. However ...
  • A fuzzy guided genetic algorithm for operon prediction 
    Elizabeth Jacob; Roschen Sasikumar; Nair, K N R (Oxford University Press, 2005)
    The operon structure of the prokaryotic genome is a critical input for the reconstruction of regulatory networks at the whole genome level. As experimental methods for the detection of operons are difficult and time-consuming, ...
  • Role of heterozygous APC mutation in niche succession and initiation of colorectal cancer - A computational study 
    Roschen Sasikumar; Rejitha, J R; Binumon, P K; Manoj, M (Public Library Science, 2011)
    Mutations in the adenomatous polyposis coli (APC) gene are found in most colorectal cancers. They cause constitutive activation of proliferative pathways when both alleles of the gene are mutated. However studies on ...