Browsing by Author "Santhoshkumar, T R"

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Lysosomal destabilization and cathepsin B contributes for cytochrome c release and caspase activation in embelin-induced apoptosis

Beena Joy; Sivadasan, R; Emilia Abraham, T; John, M; Sobhan, P K; Seervi, M; Santhoshkumar, T R (Wiley, 2010)

XIAP is an important antiapoptotic protein capable of conferring resistance to cancer cells. Embelin, the small molecular inhibitor of XIAP, possesses wide spectrum of biological activities with strong inhibition of nuclear ...
Pinocembrin triggers bax-dependent mitochondrial apoptosis in colon cancer cells

Suresh Kumar, M A; Mangalam S Nair; Hema, P S; John Mohan; Santhoshkumar, T R (Wiley, 2007)

Bioflavanoids are the major pigments in plants with multitude of biological activities including inhibition of proliferation or induction of apoptosis in tumor cells. Eventhough the safety records of most flavanoids are ...

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