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Browsing by Author "Sherin, D R"

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Exploring the cytotoxic effects of the extracts and bioactive triterpenoids from Dillenia indica against oral squamous cell carcinoma: A scientific interpretation and validation of indigenous knowledge

Aswathy, M; Banik, K; Parama, D; Sasikumar, P; Harsha, C; Joseph, A G; Sherin, D R; Thanathu, M K; Kunnumakkara, A B; Radhakrishnan, K V (American Chemical Society, 2021-04-09)

Triterpenoids are ubiquitously distributed secondary metabolites, primarily scrutinized as a source of medication and preventive measures for various chronic diseases. The ease of isolation and excellent pharmacological ...
Hexamethine Hemicyanine Dye as a Thermo-optical Probe for Serum Albumin

Udayan, S; Elizebath, D; Sherin, D R; Praveen, V K; Sunny, S; Jayamurthy, P; Manojkumar, T K; Nampoori, V P N; Thomas, S (Elsevier, 2021)

In the present work, we demonstrate the usefulness of a hexamethine hemicyanine dye as a thermo-optical probe for serum albumin, an abundant transport protein in the circulatory system, and its optimum concentration is ...
Promalabaricone B from Myristica Fatua Houtt. Seeds Demonstrate Antidiabetic Potential by Modulating Glucose Uptake via the Upregulation of AMPK in L6 Myotubes

Prabha, B; Sini, S; Sherin, D R; Neethu, S; Rameshkumar, K B; Manojkuma, T K; Jayamurthy, P; Radhakrishnan, K V (Taylor & Francis, 2021-03-04)

Promalabaricone B (PMB), an acylphenol was isolated from dichloromethane-soluble extract of the seeds of Myrisitica fatua Houtt. PMB exhibited significant inhibitory activity on a-glucosidase enzyme. The molecular docking ...
A Protoberberine Alkaloid Based Ratiometric PH-responsive Probe for the Detection of Diabetic Ketoacidosis

Meenu, M T; Cherian, A R; Sherin, D R; Nair, A R; Manojkumar, T K; Radhakrishnan, K V; Varghese, A (Elsevier, 2021-10)

Herein we report a ratiometric naturally occurring fluorescent pH probe, berberrubine (BBn) for the direct detection of diabetic ketoacidosis (DKA) conditions of patients having type I diabetes mellitus. The photophysical ...
Screening of Musa balbisiana Colla. seeds for antidiabetic properties and isolation of apiforol, a potential lead, with antidiabetic activity

Gopalan, G; Prabha, B; Joe, A; Reshmitha, T R; Sherin, D R; Abraham, B; Sabu, M; Manojkumar, T K; Radhakrishnan, K V; Nisha, P (Wiley, 2019-03-30)

BACKGROUND: 'Phytonutrients' have been reported to exert an incredible impact on the healthcare system and offer medical benefits including the prevention or treatment of lifestyle-associated diseases. We chose one of the ...

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