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Browsing by Author "Soumya, R S"

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Arsenic trioxide toxicity in H9c2 myoblasts-damage to cell organelles and possible amelioration with Boerhavia diffusa

Vineetha, V P; Prathapan, A; Soumya, R S; Raghu, K G (Springer, 2013)

Arsenic trioxide (ATO) has been long used as a chemotherapeutic agent because of its significant anticancer property. Unfortunately, the use of ATO is limited due to its cardiotoxic effects. The present study evaluates the ...
Beneficial Properties of Selenium Incorporated Guar Gum Nanoparticles Against Ischemia/ Reperfusion in Cardiomyoblasts (H9c2)

Soumya, R S; Vineetha, V P; Salin Raj, P; Raghu, K G (RSC, 2014-11)

Nanotechnology for the treatment and diagnosis has been emerging recently as a potential area of research and development. In the present study, selenium incorporated guar gum nanoparticles have been prepared by ...
Cerium nanoparticles synthesized using aqueous extract of Centella asiatica: Characterization, determination of free radical scavenging activity and evaluation of efficacy against cardiomyoblast hypertrophy

Vandana, S; Salin Raj, P; Athira, R; Soumya, R S; Raghu, K G (Royal Society of Chemistry, 2015)

Cerium nanoparticles (CeNPs) are used in biomedical applications due to their autocatalytic properties. Even though their use in the management of neurodegenerative diseases, diabetes, etc. has been reported, their role ...
Phloretin ameliorates arsenic trioxide induced mitochondrial dysfunction in H9c2 cardiomyoblasts mediated via alterations in membrane permeability and ETC complexes

Vineetha, V P; Soumya, R S; Raghu, K G (Elsevier, 2015)

Arsenic trioxide (ATO), though a very effective drug for the treatment of acute promyelocytic leukemia, leads to cardiotoxicity. As mitochondria are the center of attention of cardiac cell's general metabolic status, it ...
Polyphenol-rich apple (Malus domestica L.) peel extract attenuates arsenic trioxide induced cardiotoxicity in H9c2 cells via its antioxidant activity

Vineetha, V P; Girija, S; Soumya, R S; Raghu, K G (Royal Society of Chemistry, 2014)

Evidences suggest that apple peel has a wide range of polyphenols having antioxidant activity and its consumption has been linked with improved health benefits. Arsenic trioxide (ATO) is a very effective drug for the ...
Preparation and characterization of guar gum nanoparticles

Soumya, R S; Ghosh, S K; Emilia Abraham, T (Elsevier, 2010)

The preparation of guar gum nanoparticles by nanoprecipitation and cross-linking method is reported here Nanoparticles act as potential carries for several classes of drugs and cosmetics It has been found that the formation ...
Selenium Incorporated Guar Gum Nanoparticles Safeguard Mitochondrial Bioenergetics During Ischemia Reperfusion Injury in H9c2 Cardiac Cells

Soumya, R S; Prathapan, A; Salin Raj, P; Vineetha, V P; Raghu, K G (Elsevier, 2018-02)

The application of nanotechnology has created high impact in diagnosis and prognosis of various dis-orders including cardiovascular diseases. In the present study, we investigated the beneficial effect ofselenium incorporated ...
Synthesis, characterization and evaluation of the antioxidant potential of vanadium encapsulated guar gum nanoparticles

Soumya, R S; Reshmi, R; Jomon, S; Antu, K A; Riya, M P; Raghu, K G (Royal Society of Chemistry, 2014)

The present study investigated the antioxidant potential of guar gum macroparticles (GGMs), vanadium oxide sulphate (VS) encapsulated guar gum macroparticles (GVMs), guar gum nanoparticles (GGNs), VS encapsulated guar gum ...

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