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Browsing by Author "Syama, H P"

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Enhanced Antibacterial Metabolite Production Through the Application of Statistical Methodologies by a Streptomyces Nogalater NIIST A30 Isolated from Western Ghats Forest Soil

Jubi Jacob; Reshma, U R; Syama, H P; Jayamurthy, P; Dileep Kumar, B S (2017-04-24)

Streptomyces strains isolated from Nelliyampathy forest soil of Western Ghats, Kerala, India were evaluated for their antibacterial efficacy against two indicator pathogenic bacteria (Escherichia coli and Staphylococcus ...
Morin Inhibits Proliferation of SW480 Colorectal Cancer Cells by Inducing Apoptosis Mediated by Reactive Oxygen Species Formation and Uncoupling of Warburg Effect

Thomas, S; Arun, K B; Syama, H P; Reshmitha, T R; Nisha, P (Frontiers Media, 2017-09-12)

The study under investigation focuses on in vitro antiproliferative efficacy of the flavonoid morin and the mechanisms by which it inhibits the growth of colon cancer using SW480 colon cancer cells with emphasis on Warburg ...
Preconditioning L6 muscle cells with Naringin ameliorates oxidative stress and increases glucose uptake

Dhanya, R; Arun, K B; Nisha, V M; Syama, H P; Nisha, P; Santhosh Kumar, T R; Jayamurthy, P (PLOS, 2015-07-06)

Enhanced oxidative stress contributes to pathological changes in diabetes and its complications. Thus, strategies to reduce oxidative stress may alleviate these pathogenic processes. Herein, we have investigated Naringin ...
Quantification of Phenolics in Syzygium Cumini Seed and their Modulatory Role on Tertiary Butyl-Hydrogen Peroxide-Induced Oxidative Stress in H9c2 Cell Lines and Key Enzymes in Cardioprotection

Syama, H P; Arya, A D; Dhanya, R; Nisha, P; Sundaresan, A; Jacob, E; Jayamurthy, P (Springer, 2017-06)

The study quantified the major phenolics in different fractions of Syzygium cumini seeds and evaluated their cardioprotective efficacy. Gallic acid, ellagic acid, cinnamic acid, quercetin, syringic acid and ferulic acid ...
Rutin and quercetin enhance glucose uptake in L6 myotubes under oxidative stress induced by tertiary butyl hydrogen peroxide

Dhanya, R; Arun, K B; Syama, H P; Nisha, P; Sundaresan, A; Santhosh Kumar, T R; Jayamurthy, P (Elsevier, 2014)

Scientific evidence suggests a strong link between the oxidative stress-induced pathways and onset of diabetes and its complications. The present study evaluates the antidiabetic potential of the flavonoids, rutin and its ...
Syzygium Cumini Seed Exhibits Antidiabetic Potential via Multiple Pathways Involving Inhibition of α-Glucosidase, DPP-IV, Glycation, and Ameliorating Glucose Uptake in L6 Cell Lines

Syama, H P; Arun, K B; Sinumol, G; Dhanya, R; Anusree, S S; Nisha, P; Lankalapalli, R S; Sundaresan, A; Jayamurthy, P (Wiley, 2018-02)

The present study evaluated antidiabetic potential of fractions of Syzygium cumini seeds and identified major polyphenolic compounds in them. Potential a-glucosidase and a-amylase inhibition (IC50 1.7 and 7.62 lg/ml, ...

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