Browsing by Subject "Induced apoptosis"

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Bis(3,5-diiodo-2,4,6-trihydroxyphenyl)squaraine: A novel candidate in photodynamic therapy for skin cancer models in vivo

Gayathri Devi, D; Cibin, T R; Ramaiah, D; Annie, A (Elsevier, 2008)

Photodynamic therapy (PDT) is based on the light-induced activation of a photosensitizer generating highly reactive oxygen species that induce tissue destruction in malignant tissues. The present study was carried out to ...
Meso-tetrakis(p-sulfonatophenyl)N-confused porphyrin tetrasodium salt: a potential sensitizer for photodynamic therapy

Ajesh P Thomas; Saneesh Babu, P S; Asha Nair, S; Ramakrishnan, S; Ramaiah, D; Chandrashekar, T K; Srinivasan, A; Radhakrishna Pillai, M (American Chemical Society, 2012-06-14)

A water-soluble derivative of N-confused porphyrin (NCP) was synthesized, and the photodynamic therapeutic (PDT) application was investigated by photophysical and in vitro studies. High singlet oxygen quantum yield in ...
Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent Up-regulation of death receptors, p53, and bax

Gupta, S C; Reuter, S; Phromnoi, K; Park, B; Hema, P S; Mangalam S Nair; Aggarwal, B B (American Society for Biochemistry and Molecular Biology, 2011)

TNF-related apoptosis-inducing ligand (TRAIL) shows promise as a cancer treatment, but acquired tumor resistance to TRAIL is a roadblock. Here we investigated whether nimbolide, a limonoid, could sensitize human colon ...

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