Browsing by Subject "Tumor-necrosis-factor"

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Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis

Ajaikumar, B K; Ichikawa, H; Preetha Anand; Mohankumar, C J; Hema, P S; Mangalam S Nair; Aggarwal, B B (Amer Assoc Cancer Research, 2008)

Compounds isolated from members of the Zingiberaceae family are traditionally used as a medicine against inflammatory diseases, but little is known about the mechanism. Here, we report the isolation and structural ...
Isodeoxyelephantopin, a novel sesquiterpene lactone, potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis through suppression of nuclear factor-kappa B (NF-kappa B) activation and NF-kappa B-regulated gene expression

Ichikawa, H; Mangalam S Nair; Takada, Y; Alan Sheeja, D B; Suresh Kumar, M A; Oommen, O V; Aggarwal, B B (American Association for Cancer Research, 2006)

Purpose: Deoxyelephantopin (ESD) and isodeoxyelephantopin (ESI) are two sesquiterpene lactones derived from the medicinal plant Elephantopus scaber Linn. (Asteraceae). Although they are used for the treatment of a wide ...

Now showing items 1-2 of 2

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