Palladium-catalyzed bis-functionalization of isatylidenes: A facile route towards spiro-indol-2-ones

dc.contributor.author	George, S C
dc.contributor.author	Jubi John
dc.contributor.author	Anas, S
dc.contributor.author	Joshni John
dc.contributor.author	Yamamoto, Y
dc.contributor.author	Suresh, E
dc.contributor.author	Radhakrishnan, K V
dc.date.accessioned	2014-03-28T07:10:49Z
dc.date.available	2014-03-28T07:10:49Z
dc.date.issued	2010
dc.identifier.citation	European Journal of Organic Chemistry (28):5489-5497;Oct 2010	en_US
dc.identifier.issn	1434-193X
dc.identifier.uri	http://ir.niist.res.in:8080/jspui/handle/123456789/1246
dc.description.abstract	An effective protocol has been developed for the construction of 3,3-disubstituted indol-2-ones from isatylidenes by utilizing amphiphilic bis-pi-allylpalladium and related intermediates. The developed strategy is a new method for the quaternization of position 3 of the indol-2-one towards disubstituted functionalized indol-2-ones. These products were subjected to ring-closing metathesis towards the synthesis of spiro[cyclohexene-1,3 '-indol]-2 '-ones and spiro[oxep-5-ene-2,3 '-indol]-2 '-ones, which are of biological interest.	en_US
dc.language.iso	en	en_US
dc.publisher	Wiley	en_US
dc.subject	Allylation	en_US
dc.subject	Palladium	en_US
dc.subject	Nitrogen heterocycles	en_US
dc.subject	Spiro compounds	en_US
dc.title	Palladium-catalyzed bis-functionalization of isatylidenes: A facile route towards spiro-indol-2-ones	en_US
dc.type	Article	en_US