A facile synthesis of novel triazabicyclic molecules as potential bicyclic templates for pharmaceutical ligands by the ring opening metathesis-cross metathesis of triazatricyclo[3.2.1.0(2,6)]dec-8-ene-3,5-diones

Abstract

Novel multifunctional triazabicyclic molecules are synthesized in excellent yields by the ring opening metathesis-cross metathesis of triazatricyclo [3.2.1.0(2,6)]dec-8-ene-3,5-diones with various terminal olefins. The rigid synthesized molecules can be used as potential bicyclic templates for a number of pharmaceutically important ligands.