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A facile synthesis of novel triazabicyclic molecules as potential bicyclic templates for pharmaceutical ligands by the ring opening metathesis-cross metathesis of triazatricyclo[3.2.1.0(2,6)]dec-8-ene-3,5-diones

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dc.contributor.author Anas, S
dc.contributor.author Sarika, C
dc.contributor.author Rani, R
dc.contributor.author Radhakrishnan, K V
dc.date.accessioned 2014-05-05T06:46:55Z
dc.date.available 2014-05-05T06:46:55Z
dc.date.issued 2008
dc.identifier.citation Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry 47(7):1063-1070;Jul 2008 en_US
dc.identifier.issn 0376-4699
dc.identifier.uri http://ir.niist.res.in:8080/jspui/handle/123456789/1378
dc.description.abstract Novel multifunctional triazabicyclic molecules are synthesized in excellent yields by the ring opening metathesis-cross metathesis of triazatricyclo [3.2.1.0(2,6)]dec-8-ene-3,5-diones with various terminal olefins. The rigid synthesized molecules can be used as potential bicyclic templates for a number of pharmaceutically important ligands. en_US
dc.language.iso en en_US
dc.publisher CSIR en_US
dc.subject Ring opening metathesis-cross metathesis en_US
dc.subject Grubb's catalyst en_US
dc.subject Triazoline-diones en_US
dc.subject Triazabicyclic molecules en_US
dc.subject Peptide backbone geometry en_US
dc.subject Side-chain functionality en_US
dc.subject Domino metathesis en_US
dc.subject Olefin metathesis en_US
dc.subject Amino-acids en_US
dc.subject Thrombin inhibitors en_US
dc.subject Mimetics en_US
dc.subject Organic-synthesis en_US
dc.title A facile synthesis of novel triazabicyclic molecules as potential bicyclic templates for pharmaceutical ligands by the ring opening metathesis-cross metathesis of triazatricyclo[3.2.1.0(2,6)]dec-8-ene-3,5-diones en_US
dc.type Article en_US


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