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Strain improvement of Lactobacillus delbrueckii using nitrous acid mutation for L-lactic acid production

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dc.contributor.author Rojan P John
dc.contributor.author Nampoothiri, K M
dc.date.accessioned 2014-05-22T04:59:13Z
dc.date.available 2014-05-22T04:59:13Z
dc.date.issued 2008
dc.identifier.citation World Journal of Microbiology & Biotechnology 24(12):3105-3109;Dec 2008 en_US
dc.identifier.issn 0959-3993
dc.identifier.uri http://ir.niist.res.in:8080/jspui/handle/123456789/1422
dc.description.abstract Insertional mutagenesis is impractical in the mechanisms for protection against low ph, high solute concentration etc. Due to the involvement of large number of loci and multiple genes. An attempt was made to improve Lactobacillus delbrueckii NCIM 2025 strain by classical mutation using nitrous acid. In the present investigation, classical mutation was proved to be successful and the selected mutants had improved qualities like increased lactic acid productivity, acid tolerance and sugar tolerance. Mutants showed better growth rate and lesser generation time than the wild type. en_US
dc.language.iso en en_US
dc.publisher Springer en_US
dc.subject Acid tolerance en_US
dc.subject Lactic acid production en_US
dc.subject Lactobacillus delbrueckii en_US
dc.subject Nitrous acid mutation en_US
dc.subject Strain improvement en_US
dc.subject Solid-state fermentation en_US
dc.title Strain improvement of Lactobacillus delbrueckii using nitrous acid mutation for L-lactic acid production en_US
dc.type Article en_US


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