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Microwave assisted synthesis of novel imidazolopyridinyl indoles as potent antioxidant and antimicrobial agents

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dc.contributor.author Biradar, J S
dc.contributor.author Rajesab, P
dc.contributor.author Sasidhar, B S
dc.date.accessioned 2014-05-26T09:44:18Z
dc.date.available 2014-05-26T09:44:18Z
dc.date.issued 2014
dc.identifier.citation Journal of Chemistry:Article ID 579612; 2014 en_US
dc.identifier.issn 2090-9063
dc.identifier.uri http://ir.niist.res.in:8080/jspui/handle/123456789/1460
dc.description.abstract We describe herein the design, synthesis, and pharmacological evaluation of novel series of imidazolopyridinyl indole analogues as potent antioxidants and antimicrobials. These novel compounds (3a-i) were synthesized by reacting 3,5-disubstituted-indole-2-carboxylic acid (1a-i) with 2,3-diamino pyridine (2) in excellent yield. The novel products were confirmed by their IR, H-1 NMR, C-13 NMR, mass spectral, and analytical data. These compounds were screened for their antioxidant and antimicrobial activities. Among the compounds tested, 3a-d showed the highest total antioxidant capacity, scavenging, and antimicrobial activities. Compounds 3c-d and 3g-h have shown excellent ferric reducing activity. en_US
dc.language.iso en en_US
dc.publisher Hindawi Publishing Corporation en_US
dc.subject Imidazolopyridinyl indoles en_US
dc.subject Antioxidants en_US
dc.subject Antimicrobials en_US
dc.title Microwave assisted synthesis of novel imidazolopyridinyl indoles as potent antioxidant and antimicrobial agents en_US
dc.type Article en_US


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