Novel 1,3-dipolar cycloaddition reactions of calix[4]bis(spirodienones): synthesis of isoxazolidine derived macrocycles

dc.contributor.author	Ganga, V B
dc.contributor.author	Suresh, E
dc.contributor.author	Luxmi Varma, R
dc.date.accessioned	2015-08-06T05:49:35Z
dc.date.available	2015-08-06T05:49:35Z
dc.date.issued	2008
dc.identifier.citation	Tetrahedron Letters 49(11):1750-1752;10 Mar 2008	en_US
dc.identifier.issn	0040-4039
dc.identifier.uri	http://ir.niist.res.in:8080/jspui/handle/123456789/1903
dc.description.abstract	Calix [4]bis(spirodienones) can perform as either 4 pi or 2 pi components in cycloaddition reactions with various carbo- and heterodienophiles and with 1,2-benzoquinones leading to the formation of highly functionalized macrocycles. In this Letter we report, highly regio- and stereoselective 1,3-dipolar cycloaddition reactions of a bis(spirodienone) derivative of calix[4]arene with nitrones that provide easy access to isoxazolidine derived macrocycles in excellent yields. These isoxazolidine derivatives can be considered as direct precursors of 1,3-amino alcohols.	en_US
dc.language.iso	en	en_US
dc.publisher	Elsevier	en_US
dc.subject	Calix[4]bis(spirodienone)	en_US
dc.subject	C,N-diarylnitrone	en_US
dc.subject	1,3-dipolar cycloaddition	en_US
dc.subject	Isoxazolidine	en_US
dc.title	Novel 1,3-dipolar cycloaddition reactions of calix[4]bis(spirodienones): synthesis of isoxazolidine derived macrocycles	en_US
dc.type	Article	en_US