Abstract:
A novel organoantimony compound "(C(6)F(5))(2)SbPh" was synthesized in high yields by modified method and evaluated for insecticidal and antimicrobial activities. The compound was very effective against polyphagous insect pest of crops Spodoptera litura (Lepidoptera: Noctuidae) and polyphagous mite pest of crops Tetranychus urticae (Tetranychidae: Acari). The LC(50) value for Spodoptera litura was 0.187 (mu g/insect) and 0.385% respectively in topical application and leaf dip methods. The compound also showed very high antifeedant activity against Spodoptera litura (EC(50): 0.155%). The LC(50) value against Tetyranychus urticae was 0.021%. Antibacterial activity of the compound (1%) was also tested against human pathogenic bacteria Klebsiella pneumoniae, Staphylococcus aureus, and Pseudomonas aeruginosa showed inhibition zone of 19.78 +/- 0.44, 25.49 +/- 0.73, and 19.71 +/- 0.74 mm, respectively. The minimum inhibitory concentration (MIC) of the novel organoantimony compound against fungi Aspergillus flavus was 125 mu g/mL.
