Hydrophobic grafted and cross-linked starch nanoparticles for drug delivery

dc.contributor.author	Simi, C K
dc.contributor.author	Emilia Abraham, T
dc.date.accessioned	2015-09-12T15:04:16Z
dc.date.available	2015-09-12T15:04:16Z
dc.date.issued	2007
dc.identifier.citation	Bioprocess and Biosystems Engineering 30(3):173-180;May 2007	en_US
dc.identifier.issn	1615-7591
dc.identifier.uri	http://ir.niist.res.in:8080/jspui/handle/123456789/2031
dc.description.abstract	The synthesis of modified hydrophobic starch nanoparticles using long chain fatty acids was accomplished. Grafting of fatty acid on the starch was done using potassium persulphate as catalyst and the formation of graft polymer was confirmed by FTIR spectra. The thermal properties of the native and grafted starch were investigated using simultaneous TG-DTA and DSC. The graft polymerization was found to be depending on the temperature and the duration of the reaction. The modified starch nanoparticles were cross-linked with sodium tripoly phosphate for better stabilization. Morphology of the grafted starch nanoparticles was studied by SEM and AFM. Drug-loading and the controlled release of the drug from the nanoparticles was studied using indomethacin as model drug.	en_US
dc.language.iso	en	en_US
dc.publisher	Springer	en_US
dc.subject	Chemical modification	en_US
dc.subject	Grafting	en_US
dc.subject	Cross-linking	en_US
dc.subject	Nanoparticle	en_US
dc.subject	Controlled drug release	en_US
dc.title	Hydrophobic grafted and cross-linked starch nanoparticles for drug delivery	en_US
dc.type	Article	en_US
niist.citation