CAN-mediated stereoselective cyclization of epoxypropyl cinnamyl amines to 3,4,5-trisubstituted piperidines and supramolecular assembly of the latter aided by ethyl acetate

Abstract

The stereoselective intramolecular cyclization of epoxypropyl cinnamyl amines mediated by substoichiometric quantities of CAN leading to the synthesis of functionalized piperidines and the formation of a supramolecular assembly of the latter with ethyl acetate is described.