An Efficient and Facile Synthesis of Divergent C-3/C-5 Bis-Functionalized 2-Oxindoles from 5-Formyl-Morita-Baylis-Hillman Adducts of Oxindole

dc.contributor.author	Selvakumar, K
dc.contributor.author	Lingam, K A P
dc.contributor.author	Luxmi Varma, R
dc.contributor.author	Shanmugavelan, P
dc.date.accessioned	2016-06-03T05:50:20Z
dc.date.available	2016-06-03T05:50:20Z
dc.date.issued	2015-08
dc.identifier.citation	Journal of Chemical Sciences 127(8):1417-1426,Aug,2015	en_US
dc.identifier.uri	http://hdl.handle.net/123456789/2311
dc.description.abstract	An efficient and facile synthesis of divergent C-3/C-5 bis-functionalized 2-oxindole derivatives has been achieved from 3,5-bis-Morita-Baylis-Hillman (MBH) adducts of oxindole via nucleophilic substitution reaction for the first time. Wider scope of substrate and rate acceleration has been observed in second MBH reaction under typical reaction condition. The synthetic usefulness of bi-functionalized bis-allyl derivative has been demonstrated by the synthesis of potent bis-pyrazole via [3+2]-annulation strategy.	en_US
dc.language.iso	en	en_US
dc.publisher	Indian academy of science	en_US
dc.subject	Bis-MBH adduct; Oxindole; Nucleophilic substitution; Tri-substituted olefins; bis-pyrazole.	en_US
dc.title	An Efficient and Facile Synthesis of Divergent C-3/C-5 Bis-Functionalized 2-Oxindoles from 5-Formyl-Morita-Baylis-Hillman Adducts of Oxindole	en_US
dc.type	Article	en_US