Synthesis of Highly Functionalized Allene-Appended Oxindoles and 2-Oxo-1,2-dihydroindol-3-ylidene-2,5-dihydrofurans via Claisen Rearrangement and Cyclization

dc.contributor.author	Vaithiyanathan, V
dc.contributor.author	Selvakumar, K
dc.contributor.author	Shanmugam, P
dc.date.accessioned	2016-12-13T06:07:52Z
dc.date.available	2016-12-13T06:07:52Z
dc.date.issued	2009
dc.identifier.citation	Synlett, (10):1591-1596	en_US
dc.identifier.uri	http://hdl.handle.net/123456789/2551
dc.description.abstract	Synthesis of highly functionalized allene appended oxindole derivatives from vinyl propargyl ether derivatives of Morita-Baylis-Hillman adducts of isatin via Claisen rearrangement has been achieved. Synthetic utility of the allene derivatives obtained has been demonstrated with the synthesis of methyl 2,5-dihydro-5-methyl-2-(1-methyl-2-oxoindolin-3-ylidene)furan-3-carboxylates in a one-pot cyclization reaction under basic conditions. A plausible mechanism of the reaction is presented.	en_US
dc.language.iso	en	en_US
dc.publisher	Thieme	en_US
dc.subject	Morita-Baylis-Hillman adduct	en_US
dc.subject	Claisen rearrangement	en_US
dc.subject	isatin	en_US
dc.subject	allenes	en_US
dc.subject	vinyl propargyl ethers	en_US
dc.subject	dihydrofuran	en_US
dc.title	Synthesis of Highly Functionalized Allene-Appended Oxindoles and 2-Oxo-1,2-dihydroindol-3-ylidene-2,5-dihydrofurans via Claisen Rearrangement and Cyclization	en_US
dc.type	Article	en_US