Abstract:
A diverse approach toward the catalytic regioselective
nucleophilic addition of nitrogen heterocycles to Lewis acid
activated pentafulvenes has been established. The developed
protocol introduces pentafulvenes as nonsymmetrical alkenes for
the hydroheteroarylation reaction, providing alkylidenecyclopentenylation
at the C-3 position of indoles and the C-2 position of
pyrrole
