BF3·OEt2‑Mediated Tandem Annulation: A Strategy To Construct Functionalized Chromeno- and Pyrano-Fused Pyridines

dc.contributor.author	Ashitha, K T
dc.contributor.author	Praveen Kumar, V
dc.contributor.author	Fathimath Salfeena, C T
dc.contributor.author	Sasidhar, B S
dc.date.accessioned	2018-02-02T15:58:11Z
dc.date.available	2018-02-02T15:58:11Z
dc.date.issued	2018-01-05
dc.identifier.citation	The Journal of Organic Chemistry, 83(1):113-124	en_US
dc.identifier.uri	http://10.10.100.66:8080/xmlui/handle/123456789/2987
dc.description.abstract	A simple and efficient one-pot annulation of arylidenones, alkynes, and nitriles in the presence of BF3·OEt2 is described. A highly functionalized variety of N-substituted pyridine-fused chromeno and pyrano derivatives were obtained with satisfactory yields under mild reaction conditions. The method was proven to be valid for the synthesis of a diverse library of chromeno[3,4-c]pyridines, thiochromeno[3,4-c]pyridines, pyrano[3,4-c]pyridines, and thiopyrano[3,4-c]pyridine derivatives from readily accessible substrates. This experimentally simple protocol provides structurally complex, biologically relevant heterocycles in a one-pot operation.	en_US
dc.language.iso	en	en_US
dc.publisher	American Chemical Society	en_US
dc.title	BF3·OEt2‑Mediated Tandem Annulation: A Strategy To Construct Functionalized Chromeno- and Pyrano-Fused Pyridines	en_US
dc.type	Article	en_US