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Study on Liposomal Encapsulation of New Bodipy Sensitizers for Photodynamic Therapy

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dc.contributor.author Gayathri, T
dc.contributor.author Vijayalakshmi, A
dc.contributor.author Sreejith, M
dc.contributor.author Joshy Joseph
dc.contributor.author Madhusudhana Rao, N
dc.contributor.author Singh, S P
dc.date.accessioned 2018-06-01T11:12:43Z
dc.date.available 2018-06-01T11:12:43Z
dc.date.issued 2018-02-04
dc.identifier.citation ACS Medicinal Chemistry Letters, 9(4):323-327 en_US
dc.identifier.uri http://10.10.100.66:8080/xmlui/handle/123456789/3093
dc.description.abstract We report a series of four efficient photosensitizers (PSs) based on a Bodipy core for photodynamic therapy (PDT). In the absence of hydrophilic functional groups, these PSs have been encapsulated in liposomes and examined for photocytotoxicity against human ovarian carcinoma cell line (SK-OV- 3). The IC50 values obtained are as low as 0.350 μM, which compete with the classical photosensitizer chlorine E6 (IC50 = 0.39 μM) under similar experimental conditions. en_US
dc.language.iso en en_US
dc.publisher American Chemical Society en_US
dc.subject Bodipy, photodynamic therapy en_US
dc.subject liposomes en_US
dc.subject photosensitizer en_US
dc.subject photocytotoxicity en_US
dc.subject cancer en_US
dc.title Study on Liposomal Encapsulation of New Bodipy Sensitizers for Photodynamic Therapy en_US
dc.type Article en_US


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  • 2018
    Journal Articles authored by NIIST researchers published in 2018

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