Study on Liposomal Encapsulation of New Bodipy Sensitizers for Photodynamic Therapy

dc.contributor.author	Gayathri, T
dc.contributor.author	Vijayalakshmi, A
dc.contributor.author	Sreejith, M
dc.contributor.author	Joshy Joseph
dc.contributor.author	Madhusudhana Rao, N
dc.contributor.author	Singh, S P
dc.date.accessioned	2018-06-01T11:12:43Z
dc.date.available	2018-06-01T11:12:43Z
dc.date.issued	2018-02-04
dc.identifier.citation	ACS Medicinal Chemistry Letters, 9(4):323-327	en_US
dc.identifier.uri	http://10.10.100.66:8080/xmlui/handle/123456789/3093
dc.description.abstract	We report a series of four efficient photosensitizers (PSs) based on a Bodipy core for photodynamic therapy (PDT). In the absence of hydrophilic functional groups, these PSs have been encapsulated in liposomes and examined for photocytotoxicity against human ovarian carcinoma cell line (SK-OV- 3). The IC50 values obtained are as low as 0.350 μM, which compete with the classical photosensitizer chlorine E6 (IC50 = 0.39 μM) under similar experimental conditions.	en_US
dc.language.iso	en	en_US
dc.publisher	American Chemical Society	en_US
dc.subject	Bodipy, photodynamic therapy	en_US
dc.subject	liposomes	en_US
dc.subject	photosensitizer	en_US
dc.subject	photocytotoxicity	en_US
dc.subject	cancer	en_US
dc.title	Study on Liposomal Encapsulation of New Bodipy Sensitizers for Photodynamic Therapy	en_US
dc.type	Article	en_US