Lewis Acid Promoted Regioselective Double Hydro(hetero)arylation of 6,6′-Dialkyl-Substituted Pentafulvenes: A Facile Approach to Bisindole Derivatives

dc.contributor.author	Sasikumar, P
dc.contributor.author	Prabha, B
dc.contributor.author	Chand, S S
dc.contributor.author	Aswathy, M
dc.contributor.author	Madhukrishnan, M
dc.contributor.author	Preethanuj, P
dc.contributor.author	Suresh, E
dc.contributor.author	Jaroschik, F
dc.contributor.author	Radhakrishnan, K V
dc.date.accessioned	2018-06-21T05:52:26Z
dc.date.available	2018-06-21T05:52:26Z
dc.date.issued	2017-08-17
dc.identifier.citation	European Journal of Organic Chemistry, 2017(30):4469-4474	en_US
dc.identifier.uri	http://10.10.100.66:8080/xmlui/handle/123456789/3120
dc.description.abstract	A Lewis acid catalyzed double hydro(hetero)arylation of alkyl-substituted pentafulvenes for the synthesis of bisindolesubstituted cyclopentenoids has been developed. The scope of the reaction was explored with a wide range of indoles and pentafulvenes, and mechanistic insights were obtained. In addi-tion, we have also demonstrated a hydro(hetero)arylation–dehydroxylation reaction of 2-hydroxy-substituted pentafulvenes to afford bisindole derivatives with isoprenyl-substituted cyclopentene moieties.	en_US
dc.language.iso	en	en_US
dc.publisher	Wiley	en_US
dc.subject	Fulvenes	en_US
dc.subject	C–C coupling	en_US
dc.subject	Hydro(hetero)arylation	en_US
dc.subject	Lewis acids	en_US
dc.subject	Nitrogen heterocycles	en_US
dc.title	Lewis Acid Promoted Regioselective Double Hydro(hetero)arylation of 6,6′-Dialkyl-Substituted Pentafulvenes: A Facile Approach to Bisindole Derivatives	en_US
dc.type	Article	en_US