Metal-Free Diaryl Etherification of Tertiary Amines by Ortho-C(sp2)− H Functionalization for Synthesis of Dibenzoxazepines and -ones

dc.contributor.author	Jamsheena, V
dc.contributor.author	Mahesha, C K
dc.contributor.author	Nibin Joy, M
dc.contributor.author	Lankalapalli, R S
dc.date.accessioned	2018-07-24T05:58:26Z
dc.date.available	2018-07-24T05:58:26Z
dc.date.issued	2017-12-05
dc.identifier.citation	Organic Letters, 19(24):6614-6617	en_US
dc.identifier.uri	http://10.10.100.66:8080/xmlui/handle/123456789/3194
dc.description.abstract	A phenyliodine(III) diacetate mediated umpolung reactivity of the tertiary amines with suitably substituted o-hydroxybenzyl and phenyl groups is exploited to facilitate o- C(sp2)−H functionalization to afford diaryl ethers. The presence of an o-CHO and secondary amine functionalities in the resulting diaryl ether, generated in situ, were utilized for synthesis of dibenzoxazepines and dibenzoxazepinones. Mild conditions and relative broad substrate scope, and potential for further diversification of the diaryl ethers are highlights of this methodology.	en_US
dc.language.iso	en	en_US
dc.publisher	American Chemical Society	en_US
dc.title	Metal-Free Diaryl Etherification of Tertiary Amines by Ortho-C(sp2)− H Functionalization for Synthesis of Dibenzoxazepines and -ones	en_US
dc.type	Article	en_US