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Synthesis of 1,2,4-Trisubstituted-(1H)‑imidazoles through Cu(OTf)2‑/ I2‑Catalyzed C−C Bond Cleavage of Chalcones and Benzylamines

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dc.contributor.author Salfeena, C T F
dc.contributor.author Renjitha, J
dc.contributor.author Davis, R
dc.contributor.author Suresh, E
dc.contributor.author Sasidhar, B S
dc.date.accessioned 2018-08-21T06:52:57Z
dc.date.available 2018-08-21T06:52:57Z
dc.date.issued 2018-07
dc.identifier.citation ACS Omega, 3(7):8074–8082 en_US
dc.identifier.uri http://10.10.100.66:8080/xmlui/handle/123456789/3261
dc.description.abstract 1,2,4-Trisubstituted-(1H)-imidazoles have been synthesized by the Cu(OTf)2- and I2-catalyzed unusual C−C bond cleavage of chalcones and benzylamines. After the α,β-unsaturated C−C bond cleavage, the β-portion is eliminated from the reaction. Various aryl- and heteroarylsubstituted chalcones and benzylamines were well tolerated in this unusual transformation to yield the trisubstituted-(1H)-imidazoles. en_US
dc.language.iso en en_US
dc.publisher American Chemical Society en_US
dc.title Synthesis of 1,2,4-Trisubstituted-(1H)‑imidazoles through Cu(OTf)2‑/ I2‑Catalyzed C−C Bond Cleavage of Chalcones and Benzylamines en_US
dc.type Article en_US


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  • 2018
    Journal Articles authored by NIIST researchers published in 2018

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