Biotransformation of 5-hydroxymethylfurfural by Acinetobacter oleivorans S27 for the synthesis of furan derivatives

Abstract

Hydroxymethylfurfural (HMF) is an industrially important chemical which is a starting material in the production of plenty of platform chemicals. In this study, a complete biotransformation of HMF was achieved using a novel isolate, Acinetobacter oleivorans S27. This strain could tolerate up to 3000 mg/L of HMF concentration and convert to other furan derivatives. The conversion products includes high-value chemicals like 5hydroxymethyl-2-furancarboxylic acid (HMFCA), a known interleukin inhibitor and 2,5-furan dicarboxylic acid (FDCA), an alternate of terephthalic acid in polyester industries. The biotransformation efficiency was found to be 100%, as there is complete conversion of HMF to other chemicals. Most importantly, it is an environmental friendly process for the production of furan derivatives.