Facile Diastereoselective Synthesis of Highly Substituted Alkylene‐oxetanes from 3‐Alkyl Allenoates and Diaryl 1,2‐Diones/α‐Ketoamides Mediated by DBU

dc.contributor.author	Krishnan, J
dc.contributor.author	Mayadevi, T S
dc.contributor.author	Varughese, S
dc.contributor.author	Vijay Nair
dc.date.accessioned	2019-06-26T15:01:11Z
dc.date.available	2019-06-26T15:01:11Z
dc.date.issued	2019-02-21
dc.identifier.citation	European Journal of Organic Chemistry; 7:1557-1561	en_US
dc.identifier.uri	https://onlinelibrary.wiley.com/doi/10.1002/ejoc.201801747
dc.identifier.uri	http://10.10.100.66:8080/xmlui/handle/123456789/3372
dc.description.abstract	A facile tertiary amine‐mediated [2+2] annulation reaction of 3‐alkyl allenoates, and diaryl 1,2‐diones leading to diastereoselective synthesis of highly substituted alkylene‐oxetane derivatives is reported. The reaction was further extended to α‐ketoamides. The obtained amide‐appended oxetanes were transformed to 5‐methylene‐1H‐pyrrol‐2(5H)‐one derivatives with potential biological activity.	en_US
dc.language.iso	en	en_US
dc.publisher	Wiley	en_US
dc.subject	Zwitterions	en_US
dc.subject	Allenes	en_US
dc.subject	Cycloaddition	en_US
dc.subject	Oxygen heterocycles	en_US
dc.title	Facile Diastereoselective Synthesis of Highly Substituted Alkylene‐oxetanes from 3‐Alkyl Allenoates and Diaryl 1,2‐Diones/α‐Ketoamides Mediated by DBU	en_US
dc.type	Article	en_US