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Aphrodisiac properties of hydro‐alcoholic extract of Cassia auriculata flower in male rats

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dc.contributor.author Haripriya, V M
dc.contributor.author Dhamotharan, K
dc.contributor.author Shukla, S K
dc.contributor.author Suvekbala, V
dc.contributor.author Ragupathy, L
dc.contributor.author Kumaran, A
dc.date.accessioned 2019-07-01T14:10:47Z
dc.date.available 2019-07-01T14:10:47Z
dc.date.issued 2019-03
dc.identifier.citation Andrologia; e13180 en_US
dc.identifier.uri https://onlinelibrary.wiley.com/doi/abs/10.1111/and.13180
dc.identifier.uri http://10.10.100.66:8080/xmlui/handle/123456789/3385
dc.description.abstract Cassia auriculata is a commonly found plant in Asia, widely used in Ayurveda and Siddha medicines as a tonic, astringent and in general for diabetes. Herbal tea made from this plant has been marketed as a product for restoring sexual vitality, to increase sperm count and counteract ejaculatory disorders. However, the scientific evidences are scarce to prove this concept. Here, we examined the effect of hydroalcoholic extract obtained from C. auriculata flower upon the expression of male Wistar albino rat’s sexual behaviour. Sildenafil was used as a positive control. Penile erection index (PEI), mount latency (ML), intromission latency (IL), ejaculation latency (EL), mounting frequency (MF), intromission frequency (IF), ejaculation frequency (EF) and post‐ejaculatory interval (PEjI) were recorded for days 0, 7, 14 and 28 and also after the withdrawal of the treatment on days 7 and 15. Significant reduction in ML, IL and PEjI, and increment in EL, PEI, MF, IF and EF were observed (p < 0.05,<0.01). However, neither extract nor sildenafil sustains the effect after withdrawal of the treatment. The present finding demonstrates the aphrodisiac potential of hydroalcoholic extract of C. auriculata flower in vivo and lends support to the traditional utilisation as a sexual stimulating agent. en_US
dc.language.iso en en_US
dc.publisher Wiley en_US
dc.subject animal model en_US
dc.subject Cassia auriculata en_US
dc.subject erectile dysfunction en_US
dc.subject PDE5 en_US
dc.title Aphrodisiac properties of hydro‐alcoholic extract of Cassia auriculata flower in male rats en_US
dc.type Article en_US


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    Research articles authored by NIIST researchers published in 2019

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